The descendants of heiress and art collector Peggy Guggenheim lost their case in a French court Wednesday over her extensive collection of works housed in an 18th century palace on Venice's Grand Canal.

The French branch of the family launched legal action against the New York-based Solomon Guggenheim Foundation, which manages the collection.

The relatives are angry at the way the collection of paintings by artists including Picasso, Miro and Matisse are displayed and have called for it to be restored to its original configuration.